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However, hirsutism that occurs for this reason will generally be. Fat cells produce estrogen as well as the ovaries and excess fat can cause estrogen dominance, which can lead to a hormone imbalance. Too much testosterone can also indicate the presence of tumors on the adrenal gland or ovaries—the main production center for these hormones. If the ovaries produce too much androgen (hormones such as testosterone), a woman may develop male characteristics. This ovarian imbalance can be caused by. Stromal cell cancers of the ovaries are rare and grow slowly. They secrete estrogen and testosterone. Excess testosterone can cause acne and facial hair J Sex Med 2016; 13: 1029. Paduch DA, Brannigan RE, Fuchs EF et al: The laboratory diagnosis of testosterone deficiency, high testosterone ovarian cancer. Urology 2014; 83: 980. 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